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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1364668Generated: October 31, 2026

Isopropylamine → N1-(4-chloro-3-(pyridin-2-yl)phenyl)-N4-isopropylterephthalamide

https://huagongshe.com/reaction/1364668

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsopropylamineHCID 6363—
Reactant4-(4-Chloro-3-(pyridin-2-yl)phenylcarbamoyl)benzoic acidHCID 66877887—
ProductN1-(4-chloro-3-(pyridin-2-yl)phenyl)-N4-isopropylterephthalamideHCID 58614667—

Reaction Steps

50 mg of 4-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)benzoic acid was coupled to isopropylamine via Procedure G. The product was purified on reverse phase HPLC to yield N1-(4-chloro-3-(pyridin-2-yl)phenyl)-N4-isopropylterephthalamide. MS (Q1) 394 (M)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07888364B2
Source datasetuspto-grants-2011_02
ORD IDord-9fb041588d1644cb9e1cc00bc914d335
Source noteuspto-grants-2011_02