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HRID1364723

反应详情

EQUATION

反应方程式

HRID 1364723 的结构方程式

REACTANTS

反应物

2
结构：C1CNCCNC1
HCID68163

1H-1,4-Diazepine, hexahydro-

C5H12N2

结构：O=C(Nc1ccc(Cl)c(-c2ccccn2)c1)c1ccc(Cl)nc1
HCID58614810

6-Chloro-N-[4-chloro-3-(pyridin-2-yl)phenyl]pyridine-3-carboxamide

C17H11Cl2N3O

PRODUCTS

生成物

1
结构：O=C(Nc1ccc(Cl)c(-c2ccccn2)c1)c1ccc(N2CCCNCC2)nc1
HCID58614792

未命名化合物

PROCEDURE

实验过程

50 mg of 6-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)nicotinamide was reacted with 1,4-diazepane via Procedure F. The reaction was evaporated to dryness and purified on reverse phase HPLC to yield N-(4-chloro-3-(pyridin-2-yl)phenyl)-6-(1,4-diazepan-1-yl)nicotinamide. MS (Q1) 408 (M)+.

WORKUP

后处理

  1. customThe reaction was evaporated to dryness
  2. custompurified on reverse phase HPLC