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HRID1364727

反应详情

EQUATION

反应方程式

HRID 1364727 的结构方程式

REACTANTS

反应物

2
结构：CS(=O)(=O)c1ccc(CN)cc1
HCID57421

4-Methylsulfonylbenzylamine

C8H11NO2S

结构：O=C(O)c1ccc(C(=O)Nc2ccc(Cl)c(-c3ccccn3)c2)c(Cl)c1
HCID66878605

未命名化合物

PRODUCTS

生成物

1
结构：CS(=O)(=O)c1ccc(CNC(=O)c2ccc(C(=O)Nc3ccc(Cl)c(-c4ccccn4)c3)c(Cl)c2)cc1
HCID58614647

未命名化合物

PROCEDURE

实验过程

62 mg of 3-chloro-4-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)benzoic acid was coupled to (4-(methylsulfonyl)phenyl)methanamine via Procedure G. The crude product was purified on reverse phase HPLC to yield 2-chloro-N1-(4-chloro-3-(pyridin-2-yl)phenyl)-N4-(4-(methylsulfonyl)benzyl)terephthalamide. MS (Q1) 554 (M)+.

WORKUP

后处理

  1. customThe crude product was purified on reverse phase HPLC