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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1364752Generated: October 31, 2026

4-(Aminomethyl)piperidine → HCID 58614769, compound

https://huagongshe.com/reaction/1364752

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Aminomethyl)piperidineHCID 23527—
Reactant3-Chloro-4-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)benzoic acidHCID 66878605—
ProductHCID 58614769HCID 58614769—

Reaction Steps

50 mg of 3-chloro-4-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)benzoic acid was coupled to piperidin-4-ylmethanamine via Procedure G. The crude product was purified on reverse phase HPLC to yield 2-chloro-N1-(4-chloro-3-(pyridin-2-yl)phenyl)-N4-(piperidin-4-ylmethyl)terephthalamide. MS (Q1) 483 (M)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07888364B2
Source datasetuspto-grants-2011_02
ORD IDord-f142317e9d644d909b51c748fe942b1b
Source noteuspto-grants-2011_02