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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1364791Generated: November 3, 2026

Methylamine hydrochloride → HCID 58614915, compound

https://huagongshe.com/reaction/1364791

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamine hydrochlorideHCID 6364545—
ReactantHCID 66877818HCID 66877818—
ReactantHCID 86603991HCID 86603991—
ProductHCID 58614915HCID 58614915—

Reaction Steps

120 mg of 6-(2-chloro-5-(2-methyl-6-(trifluoromethyl)nicotinamido)phenyl)nicotinate was hydrolyzed via Procedure M. 112 mg of 6-(2-chloro-5-(2-methyl-6-(trifluoromethyl)nicotinamido)phenyl)nicotinic acid was coupled to Methylamine Hydrochloride via Procedure G and purified by reverse phase HPLC to give pure N-(4-chloro-3-(5-(methylcarbamoyl)pyridin-2-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide. MS (Q1) 449 (M)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07888364B2
Source datasetuspto-grants-2011_02
ORD IDord-e71921a92cac47b588f95e34badd419c
Source noteuspto-grants-2011_02