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HRID1364887

反应详情

EQUATION

反应方程式

HRID 1364887 的结构方程式

REACTANTS

反应物

2
结构：Cc1c(C(=O)O)cnn1-c1ccc(F)cc1
HCID4270263

1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acid

C11H9FN2O2

结构：Nc1ccc(Cl)c(-c2ccccn2)c1
HCID40151925

4-Chloro-3-(pyridin-2-yl)aniline

C11H9ClN2

PRODUCTS

生成物

1
结构：Cc1c(C(=O)Nc2ccc(Cl)c(-c3ccccn3)c2)cnn1-c1ccc(F)cc1
HCID58614761

未命名化合物

PROCEDURE

实验过程

50 mg of 4-chloro-3-(pyridin-2-yl)aniline was coupled to 1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acid via Procedure G. The product was purified on reverse phase HPLC to yield N-(4-chloro-3-(pyridin-2-yl)phenyl)-1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxamide. MS (Q1) 407.0 (M)+.

WORKUP

后处理

  1. customThe product was purified on reverse phase HPLC