HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → Methyl 3-amino-4-iodobenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-Amino-4-iodobenzoic acid | HCID 11807503 | — |
| Product | Methyl 3-amino-4-iodobenzoate | HCID 21628210 | — |
Reaction Steps
3-Amino-4-iodobenzoic acid (13.35 g, 50.8 mmol) was added to MeOH (150 mL) and SOCl2 (4.8 mL, 65.8 mmol, 1.3 equivalent) was added. The mixture was refluxed for 3 h and then volatiles were removed under reduced pressure. The residue was co-evaporated 3× with MeOH and dried in vacuo (15.23 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07888363B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-7f58fbb9f3b047d9bf16ddc8a8e0c703 |
| Source note | uspto-grants-2011_02 |