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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1365005Generated: October 27, 2026

3,5-Dimethylisoxazole-4-isocyanate → 1-(3,5-Dimethylisoxazol-4-yl)carbamoylcyclopropanesulfonamide tert-butylcarbamate

https://huagongshe.com/reaction/1365005

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Dimethylisoxazole-4-isocyanateHCID 2736266—
Reactant1-Methoxymethylcyclopropylsulfonylamine tert-butylcarbamateHCID 66752382—
Product1-(3,5-Dimethylisoxazol-4-yl)carbamoylcyclopropanesulfonamide tert-butylcarbamateHCID 66752480100%

Reaction Steps

This compound was obtained in a crude 100% yield according to the procedure described for the synthesis of 1-methoxymethylcyclopropylsulfonylamine tert-butylcarbamate except that 1.20 equivalents of 3,5-dimethylisoxazole-4-isocyanate was used as the electrophile. The compound was taken directly into the next reaction without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07888464B2
Source datasetuspto-grants-2011_02
ORD IDord-d2004d0b15534cc58ca6d70a6ff870ef
Source noteuspto-grants-2011_02