HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → [4-(2-Methylpropyl)phenyl]methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Benzaldehyde, 4-(2-methylpropyl)- | HCID 577537 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | [4-(2-Methylpropyl)phenyl]methanol | HCID 14620446 | 94.7% |
Reaction Steps
To a solution of 4-isobutylbenzaldehyde (2.4 g) in methanol (10 mL) was added sodium borohydride (0.85 g) at room temperature, and the mixture was stirred at room temperature overnight. Water was added to the reaction mixture, and the mixture was extracted with diethyl ether. The organic layer was washed with water and brine, and dried over anhydrous magnesium sulfate. The solvent was removed under reduced pressure to give the title compound (2.3 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07888487B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-25c886ccb1fc4f2cbe5baa6204761d0a |
| Source note | uspto-grants-2011_02 |