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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1365104Generated: October 25, 2026

Ethanolamine → 2-Benzamidoethanol

https://huagongshe.com/reaction/1365104

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolamineHCID 700—
ReactantMethyl BenzoateHCID 7150—
SolventDichloromethaneHCID 6344—
Product2-BenzamidoethanolHCID 56952611%

Reaction Steps

Under an argon atmosphere, a mixture of methyl benzoate (3.0 mmol), 2-aminoethanol (3.6 mmol), Zn4(OCOCF3)6O (0.15 mmol) and methylene chloride (2.5 mL) was stirred at room temperature for 3 days, and as a result, N-(2-hydroxyethyl)benzamide was obtained in 11% yield. The resulting compound was identified by comparison with physical property data of the known compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07888513B2
Source datasetuspto-grants-2011_02
ORD IDord-a663e7c8c7dd41ad88739b85d439c8fd
Source noteuspto-grants-2011_02