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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 136524Generated: October 30, 2026

Dichloromethane → 4-(4-bromo-2-methylpyrazol-3-yl)-N-[1-(1,3-dioxoisoindol-2-yl)-3-[2-(trifluoromethyl)phenyl]propan-2-yl]-5-ethylthiophene-2-carboxamide

https://huagongshe.com/reaction/136524

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantHexafluorophosphateHCID 9886—
ReactantDiisopropylethylamineHCID 81531—
ReactantBromotripyrrolidin-1-ylphosphoniumHCID 2733180—
Reactant4-(4-bromo-1-methyl-1H-pyrazol-5-yl)-5-ethyl-2-thiophenecarboxylic acidHCID 57826786—
Reactant2-[2-amino-3-[2-(trifluoromethyl)phenyl]propyl]isoindole-1,3-dioneHCID 178510762—
Product4-(4-bromo-2-methylpyrazol-3-yl)-N-[1-(1,3-dioxoisoindol-2-yl)-3-[2-(trifluoromethyl)phenyl]propan-2-yl]-5-ethylthiophene-2-carboxamideHCID 76576392—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-0874b3d394f64171a9df5c311251697c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)