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HRID1365406

反应详情

EQUATION

反应方程式

HRID 1365406 的结构方程式

REACTANTS

反应物

2
结构：CS(=O)(=O)N1CCN(Cc2cc3c(N4CCOCC4)nc(Cl)nc3s2)CC1
HCID56833946

未命名化合物

结构：CC1(C)OB(c2cnc(N)c(Cl)c2)OC1(C)C
HCID59619973

3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine

C11H16BClN2O2

PRODUCTS

生成物

1
结构：CS(=O)(=O)N1CCN(Cc2cc3c(N4CCOCC4)nc(-c4cnc(N)c(Cl)c4)nc3s2)CC1
HCID58233998

未命名化合物

收率 89.8%

PROCEDURE

实验过程

4-(2-chloro-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[2,3-d]pyrimidin-4-yl)morpholine (0.8 g, 1.7 mmol) was reacted with 3-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine (0.6 g) according to General Procedure Suzuki to provide 376 (0.8 g) following silica gel purification (0-15% MeOH in CH2Cl2) MS (Q1) 524 (M)+.