Bromine → 1-(4-Bromophenyl)cyclopropane-1-carboxylic acid

Participants

Reaction Conditions

Reaction Steps

At 5° C. bromine (1.5 mL, 30 mmol) is added dropwise to a solution of 1-phenyl-1-cyclopropylcarboxylic acid (5 g, 30 mmol) and sodiumacetate (2.7 g, 33 mmol) in 30 mL glacial acetic acid. Then the mixture is heated to 50° C. and stirred for 2 days. The reaction mixture is diluted with 100 mL water, and the precipitate formed is filtered off and washed with 50% acetic acid. Yield: 5.7 g.

Provenance & Evidence