Aluminium lithium hydride → HCID 59703212, compound

Participants

Reaction Steps

Under an argon atmosphere at −78° C. a solution of lithium aluminium hydride (1 M in THF, 3 mL) is added to a solution of 4-(7-amino-3-pyridin-3-yl-4,5-dihydro-pyrazolo[4,3-g]benzothiazol-1-yl)-3-chloro-N,N-dimethylbenzamide (PCT/EP05055021) (0.46 g, 1 mmol) in 25 mL dry THF. After 5 min the cooling bath is removed and the reaction mixture is heated to RT. Then while cooling, 1 mL of water is added dropwise and the mixture is stirred for 30 min. The precipitate is filtered and the filtrate evaporated down.

Provenance & Evidence