Trimethylsilyl iodide → HCID 24783366, compound

Participants

Reaction Conditions

Reaction Steps

The product of step (e) (diastereomer 1 and diastereomer 2, separately, 20 mg, 0.06 mmol) was dissolved in 3 mL CHCl3 and treated with TMSI (40 μL, 0.29 mmol). After heating to 70° C. overnight, the reaction was quenched with MeOH (5 mL) and 1 M NaOH (2 mL). The title compound was extracted into CHCl3 (2×10 mL) and subsequently purified by preparative HPLC-MS.

Provenance & Evidence