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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1365656Generated: October 30, 2026

1-Bromo-2-methylpropane → HCID 57762509, compound

https://huagongshe.com/reaction/1365656

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-2-methylpropaneHCID 6555—
ReactantSodium hydrideHCID 24758—
ReactantN-(4-iodophenyl)pyrimidin-2-amineHCID 57762548—
ProductHCID 57762509HCID 5776250993.6%

Reaction Steps

In the same manner as in Reference Example 13, N-(4-iodophenyl)pyrimidin-2-amine (150 mg) and isobutyl bromide (83 mg) were reacted in the presence of sodium hydride to obtain N-(4-iodophenyl)-N-isobutylpyrimidin-2-amine (167 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07893046B2
Source datasetuspto-grants-2011_02
ORD IDord-4d0d9f1a7b274e6c815ef07e0d1cec84
Source noteuspto-grants-2011_02