HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2,6-Dichlorobenzamido)pent-4-enoic acid methyl ester → HCID 57762580, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2,6-Dichlorobenzamido)pent-4-enoic acid methyl ester | HCID 57762518 | — |
| Reactant | HCID 57762546 | HCID 57762546 | — |
| Product | HCID 57762580 | HCID 57762580 | 51.5% |
Reaction Steps
In the same manner as in Example 1, 2-(2,6-dichlorobenzamido)pent-4-enoic acid methyl ester (145 mg) was reacted with N-(4-iodophenyl)-N-(3-methyl-2-butenyl)pyrimidin-2-amine (175 mg) to obtain (E)-2-(2,6-dichlorobenzamido)-5-[4-((3-methyl-2-butenyl)-pyrimidin-2-ylamino)phenyl]pent-4-enoic acid methyl ester (133 mg). Column chromatography (silica gel, eluent: hexane/ethyl acetate=1/1) was used for purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07893046B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-f65d957421d2469c9ccce6493226d90c |
| Source note | uspto-grants-2011_02 |