HCID 72346776, compound → HCID 55283784, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 5-(methylthio)furan-2-carbaldehyde oxime (220 mg, 1.40 mmol) in glacial acetic acid (15 mL) was added zinc dust (2.10 g, 32.2 mmol) and the reaction mixture was stirred at 23° C. for 4 h. After filtration on celite, the acetic acid was concentrated in vacuo and the crude material purified on functionalized silica gel (6 g) containing sulfonic acid (0.8 mmol/g) to afford 138 mg (69%) of the title compound as an orange oil. 1H NMR (400 MHz, CDCl3): 6.36 (1H, d, J=3.2 Hz), 6.11 (1H, d, J=3.2 Hz), 3.80 (2H, s), 2.36 (3H, s).

Provenance & Evidence