HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline → HCID 25253994, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline | HCID 10848590 | — |
| Reactant | HCID 86630069 | HCID 86630069 | — |
| Product | HCID 25253994 | HCID 25253994 | 35.7% |
Reaction Steps
1-[4-(5-Chloro-7-morpholin-4-yl-thiazolo[5,4-d]pyrimidin-2-ylmethyl)-piperazin-1-yl]-2-hydroxy-propan-1-one (100 mg) was reacted with 72 mg of 3-(4,4,5,5-tetramethyl-1,3,2,-dioxaborolan-2-yl)quinoline via General Procedure A. The product was purified by reverse phase HPLC to yield 43.5 mg of 106. MS (Q1) 520.3 (M)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07893059B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-2fff77945a5c4b8fa5dd9c7ccb6d8ce4 |
| Source note | uspto-grants-2011_02 |