HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Aminopyrimidin-5-yl)boronic acid → HCID 25253996, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Aminopyrimidin-5-yl)boronic acid | HCID 17750211 | — |
| Reactant | HCID 86630069 | HCID 86630069 | — |
| Product | HCID 25253996 | HCID 25253996 | 24.6% |
Reaction Steps
1-[4-(5-Chloro-7-morpholin-4-yl-thiazolo[5,4-d]pyrimidin-2-ylmethyl)-piperazin-1-yl]-2-hydroxy-propan-1-one (100 mg) was reacted with 62 mg of 2-aminopyrimidine-5-boronic acid, pinacol ester via General Procedure A. The product was purified by reverse phase HPLC to yield 28 mg of 108. MS (Q1) 486.2 (M)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07893059B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-a137d97f524d4e668464e215769aea9b |
| Source note | uspto-grants-2011_02 |