Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline → HCID 25254152, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline | HCID 10848590 | — |
| 반응물 | 5-Chloro-2-((4-methylsulfonylpiperazin-1-yl)methyl)-7-morpholinothiazolo[5,4-d]pyrimidine | HCID 44541675 | — |
| 생성물 | HCID 25254152 | HCID 25254152 | 46% |
반응 단계
5-Chloro-2-(4-methanesulfonyl-piperazin-1-ylmethyl)-7-morpholin-4-yl-thiazolo[5,4-d]pyrimidine (130 mg) was reacted with 92 mg of 3-(4,4,5,5-tetramethyl-1,3,2,-dioxaborolan-2-yl)quinoline via General Procedure A. The product was purified by reverse phase HPLC to yield 72.6 mg of 112. MS (Q1) 526.2 (M)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07893059B2 |
| 출처 데이터셋 | uspto-grants-2011_02 |
| ORD ID | ord-31da31446c834a62a43cc7e60926b649 |
| 출처 메모 | uspto-grants-2011_02 |