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HRID1365803

反应详情

EQUATION

反应方程式

HRID 1365803 的结构方程式

REACTANTS

反应物

2
结构：CC1(C)OB(c2ccc(NS(C)(=O)=O)cc2)OC1(C)C
HCID16217653

N-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanesulfonamide

C13H20BNO4S

结构：Clc1nc(N2CCOCC2)c2nc(I)sc2n1
HCID25210284

未命名化合物

PRODUCTS

生成物

1
结构：CS(=O)(=O)Nc1ccc(-c2nc3c(N4CCOCC4)nc(Cl)nc3s2)cc1
HCID86630075

未命名化合物

PROCEDURE

实验过程

4-(5-Chloro-2-iodothiazolo[5,4-d]pyrimidin-7-yl)morpholine 18 was reacted with N-methylsulfonyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine via General Procedure A to give crude 4-(5-chloro-7-morpholinothiazolo[5,4-d]pyrimidin-2-yl)-N-methylsulfonylbenzenamine, which was then reacted with 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine via General Procedure A again to give 125 after purification by reverse HPLC. MS (Q1) 485 (M+)