5,7-Dichloro-2-methylthiazolo[5,4-d]pyrimidine → 5,7-Dichloro-2-methylthiazolo[4,5-d]pyrimidine

HRID 1365844Notes

Reaction equation

HRID 1365844 reaction equation
[Cl:1][C:2]1[N:3]=[C:4]([Cl:12])[C:5]2N=C(C)S[C:6]=2[N:7]=1.[CH3:13][C:14]1[S:15]C2C(=O)NC(=O)NC=2[N:24]=1>>[Cl:1][C:2]1[N:3]=[C:4]([Cl:12])[C:5]2[S:15][C:14]([CH3:13])=[N:24][C:6]=2[N:7]=1

Participants

3

Reactant 2

HCID 3456395,7-Dichloro-2-methylthiazolo[5,4-d]pyrimidineHCID 3456412-Methylthiazolo[4,5-d]pyrimidine-5,7(4H,6H)-dione

Product 1

HCID 582349525,7-Dichloro-2-methylthiazolo[4,5-d]pyrimidine

Procedure

Prepared using the method used in the preparation of 5,7-dichloro-2-methyl-thiazolo[5,4-d]pyrimidine using 2-methyl-4H-thiazolo[4,5-d]pyrimidine-5,7-dione in place of 2-methyl-4H-thiazolo[5,4-d]pyrimidine-5,7-dione. The title compound was obtained as an solid (140 mg, 28%).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-e30491ec6458450b9106e1b91d296301
Source dataset
uspto-grants-2011_02
Patent number
US07893060B2

Reaction notes

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