HCID 58748417, compound → HCID 58748479, compound

HRID 1366278Notes

Reaction equation

HRID 1366278 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][C:12]([CH3:15])=[C:11]([N+:16]([O-])=O)[CH:10]=2)=[CH:5][CH:4]=1>[Pd].CO>[NH2:16][C:11]1[CH:10]=[C:9]([C:6]2[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)[CH:14]=[CH:13][C:12]=1[CH3:15]

Participants

4

Reactant 1

HCID 58748417HCID 58748417, compound

Product 1

HCID 58748479HCID 58748479, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A suspension of 4′-methoxy-4-methyl-3-nitrobiphenyl (630 mg, 2.95 mmol) and 10% palladium on charcoal (63 mg, 0.059 mmol) in methanol (6 mL) is stirred under hydrogen atmosphere for 12 hours. Palladium catalyst is removed by filtration and the resulting solution is evaporated in vacuo to afford the title compound.

Workup

  1. customPalladium catalyst is removed by filtration
  2. customthe resulting solution is evaporated in vacuo

Sources & evidence

ORD record
ord-2a3afa795e624a5e8cb803fd044f5398
Source dataset
uspto-grants-2011_02
Patent number
US07893074B2

Reaction notes

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