反应详情

The titled compound above was prepared using the same procedure as that used for the synthesis of {4-[(2R,3R)-3-{[2-(2,3-dihydro-1H-inden-5-yl)-2-oxoethyl]thio}-1-(4-fluorophenyl)-4-oxoazetidin-2-yl]phenoxy}acetic acid but using 2-bromo-1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethanone instead of 2-bromo-1-(2,3-dihydro-1H-inden-5-yl)ethanone. 1H NMR [(CD3)2SO), 400 MHz]δ 1.66-1.75 (m, 4H), 2.66-2.77 (m, 4H), 4.22-4.31 (m, 3H), 4.62 (s, 2H), 5.11 (d, 1H), 6.86-7.61 (m, 11H).