HCID 86636951, compound → HCID 58000525, compound

Participants

Reaction Steps

A solution of [(2R)-2-(cyclopentylmethyl)-3-(2-{6-[(2S)-2,4-dimethyl-1-piperazinyl]-5-fluoro-2-methyl-4-pyrimidinyl}hydrazino)-3-oxopropyl][(phenylmethyl)oxy]formamide (0.118 g, 0.22 mmol) and Pd(C) (0.018 g) in MeOH (10 mL) was treated as in General Procedure A, Part C, to provide [(2R)-2-(cyclopentylmethyl)-3-(2-{6-[(2S)-2,4-dimethyl-1-piperazinyl]-5-fluoro-2-methyl-4-pyrimidinyl}hydrazino)-3-oxopropyl]hydroxyformamide as a white solid (0.089 g, 91%). LCMS: (M+H)+=452.4.

Provenance & Evidence