Benzyl 4-(dimethylamino)-3,3-dimethylpyrrolidine-1-carboxylate → HCID 55299466, compound

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Reaction Steps

To a solution of racemic phenylmethyl 4-(dimethylamino)-3,3-dimethyl-1-pyrrolidinecarboxylate (assumed 0.6565 g, 2.376 mmol) in MeOH was added 10% Pd/C (50% water, 195 mg). The mixture was hydrogenated under balloon pressure for 1 h, and then filtered. The solution was concentrated in vacuo to afford racemic N,N,4,4-tetramethyl-3-pyrrolidinamine (0.3479 g, quantitative yield) as an almost colorless oil. LCMS: (M+H)+: 143.1.

Provenance & Evidence