Hydrochloric Acid → HCID 66936091, compound

Participants

Reaction Steps

To a degassed solution of (rac)-cis-1,1,2-trimethyl-5-(phenylmethyl)octahydropyrrolo[3,4-c]pyrrole (1.44 g, 6 mmol) in MeOH (30 mL) was added 1 M HCl (12.3 mL, 12 mmol) followed by 10% Pd/C (220 mg). The resulting mixture was stirred overnight under a hydrogen balloon. Filtration of the catalyst and evaporation of the solvents in vacuo yielded (rac)-cis-1,1,2-trimethyloctahydropyrrolo[3,4-c]pyrrole in quantitative yield as a hydrochloride salt. LCMS: (M+H)+: 155.1.

Provenance & Evidence