Hydrochloric Acid → HCID 66936571, compound

Participants

Reaction Steps

N,N-Diethyl-1-(phenylmethyl)-L-prolinamide (1.603 g, 6.156 mmol) was dissolved in a mixture of MeOH (50 mL) and 1N HCl (14 mL, 14 mmol), degassed and placed under argon. 10% Pd/C (480 mg) was added, and the contents were thoroughly degassed and placed under a hydrogen balloon for 2 h. The contents were then degassed, and the Pd/C was removed by filtration through a fiberglass filter, washing with MeOH. The filtrate was concentrated in vacuo to provide pure N,N-diethyl-L-prolinamide hydrochloride (1.658 g, >99%). LCMS: (M+H)+: 171.1.

Provenance & Evidence