反应详情

Phenylmethyl (3S)-3-{[(methyloxy)carbonyl]amino}-1-pyrrolidinecarboxylate (2.00 g, 7.19 mmol) was dissolved in degassed methanol (20 mL) and Pd/C (0.4 g, 0.376 mmol) was added. The reaction vessel was evacuated and back-filled with hydrogen via a balloon. The reaction was stirred for 2 h after which time the catalyst was removed by filtration through Celite. Evaporation of the solvent yielded methyl (3S)-3-pyrrolidinylcarbamate (0.99 g, 76%) as a clear oil.

1. customThe reaction vessel was evacuated
2. additionback-filled with hydrogen via a balloon
3. customwas removed by filtration through Celite
4. customEvaporation of the solvent