HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1366804Generated: November 1, 2026
Methyl 4-(bromomethyl)benzoate → HCID 57637614, compound
https://huagongshe.com/reaction/1366804
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methyl 4-(bromomethyl)benzoate | HCID 256687 | — |
| Reactant | Sodium 4-(1-BOC-piperazin-4-yl)phenoxide | HCID 57637585 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 57637614 | HCID 57637614 | — |
Reaction Steps
Sodium 4-(1-BOC-piperazin-4-yl)phenoxide (1 equivalent) and methyl 4-bromomethylbenzoate (1 equivalent) were combined in dry acetone and heated to reflux at 60° C. for 18 hours. The slurry was filtered and the filtrate was then concentrated to provide the crude methyl 4-[4-(1-BOC-piperazin-4-yl)phenoxymethyl]benzoate, that was used without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07893096B2 |
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| Source dataset | uspto-grants-2011_02 |
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| ORD ID | ord-f3a436dbe47c46f9804cc512cdc9913e |
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| Source note | uspto-grants-2011_02 |
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