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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1366976Generated: October 30, 2026

Trifluoroacetic acid → HCID 23146261, compound

https://huagongshe.com/reaction/1366976

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantPotassium CarbonateHCID 11430—
ReactantHCID 86625768HCID 86625768—
SolventDichloromethaneHCID 6344—
ProductHCID 23146261HCID 2314626129.3%

Reaction Steps

(RS)-2-Benzooxazol-2-ylmethyl-piperidine-1-carboxylic acid tert butyl ester (0.50 g) in dichloromethane (8 ml) was cooled (ice-bath) and trifluoroacetic acid (2 ml) added. The mixture was stirred with ice-cooling for 4 h, poured onto saturated potassium carbonate (20 ml) and extracted with dichloromethane. The combined extracts were dried (MgSO4) and solvent removed at reduced pressure to give the title compound (0.10 g)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07893090B2
Source datasetuspto-grants-2011_02
ORD IDord-3bf6c4c66f5a4266b36f18de1b5d1008
Source noteuspto-grants-2011_02