Benzofuran, 5-bromo- → HCID 66968171, compound

HRID 1367009Notes

Reaction equation

HRID 1367009 reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][CH:8]=[CH:7][C:6]=2[CH:10]=1.[C:11]([O:15][C:16]([N:18]1[CH2:23][CH2:22][CH2:21][CH2:20][CH:19]1[C:24](=[O:29])N(OC)C)=[O:17])([CH3:14])([CH3:13])[CH3:12]>>[C:11]([O:15][C:16]([N:18]1[CH2:23][CH2:22][CH2:21][CH2:20][CH:19]1[C:24]([C:8]1[O:9][C:5]2[CH:4]=[CH:3][C:2]([Br:1])=[CH:10][C:6]=2[CH:7]=1)=[O:29])=[O:17])([CH3:14])([CH3:13])[CH3:12]

Participants

3

Reactant 2

HCID 90015Benzofuran, 5-bromo-HCID 21988510tert-Butyl 2-(methoxy(methyl)carbamoyl)piperidine-1-carboxylate

Product 1

HCID 66968171HCID 66968171, compound

Procedure

The title compound (0.96 g) was prepared from 5-bromo-benzofuran (3.6 g, prepared according to procedures similar to those described in Synth. Commun., 257, (1989)) and (RS)-1-(tert-butyloxycarbonyl)-2-(N-methoxy-N-methylcarbamoyl)-piperidine, D1 (4.9 g) according to a procedure similar to that for Description 2.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-31253dcc581d4e78b86ec1bf7f5a1f64
Source dataset
uspto-grants-2011_02
Patent number
US07893090B2

Reaction notes

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