tert-Butyl 2-(methoxy(methyl)carbamoyl)piperidine-1-carboxylate → HCID 66968468, compound

HRID 1367012Notes

Reaction equation

HRID 1367012 reaction equation
[F:1][C:2]1[C:7]2[CH:8]=[CH:9][O:10][C:6]=2[CH:5]=[CH:4][CH:3]=1.[C:11]([O:15][C:16]([N:18]1[CH2:23][CH2:22][CH2:21][CH2:20][CH:19]1[C:24](=[O:29])N(OC)C)=[O:17])([CH3:14])([CH3:13])[CH3:12]>>[C:11]([O:15][C:16]([N:18]1[CH2:23][CH2:22][CH2:21][CH2:20][CH:19]1[C:24]([C:9]1[O:10][C:6]2[CH:5]=[CH:4][CH:3]=[C:2]([F:1])[C:7]=2[CH:8]=1)=[O:29])=[O:17])([CH3:14])([CH3:13])[CH3:12]

Participants

3

Reactant 2

HCID 21988510tert-Butyl 2-(methoxy(methyl)carbamoyl)piperidine-1-carboxylateHCID 222231104-Fluoro-1-benzofuran

Product 1

HCID 66968468HCID 66968468, compound

Procedure

The title compound (500 mg) was prepared from 4-fluoro-benzofuran (450 mg) and (RS)-1-(tert-butyloxycarbonyl)-2-(N-methoxy-N-methylcarbamoyl)-piperidine, D1 (900 mg) according to a procedure similar to that for Description 2.

Sources & evidence

ORD record
ord-54c7729551ac4f59b8da86cb7d448d58
Source dataset
uspto-grants-2011_02
Patent number
US07893090B2

Reaction notes

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