4-(4-fluorophenyl)-1-methyl-1H-pyrazole-3-carboxylic acid → HCID 17973701, compound

HRID 1367027Notes

Reaction equation

HRID 1367027 reaction equation
[NH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH:2]1[CH2:7][C:8]1[S:9][C:10]2[CH:16]=[CH:15][CH:14]=[CH:13][C:11]=2[N:12]=1.[F:17][C:18]1[CH:23]=[CH:22][C:21]([C:24]2[C:25]([C:30](O)=[O:31])=[N:26][N:27]([CH3:29])[CH:28]=2)=[CH:20][CH:19]=1>>[S:9]1[C:10]2[CH:16]=[CH:15][CH:14]=[CH:13][C:11]=2[N:12]=[C:8]1[CH2:7][CH:2]1[CH2:3][CH2:4][CH2:5][CH2:6][N:1]1[C:30]([C:25]1[C:24]([C:21]2[CH:22]=[CH:23][C:18]([F:17])=[CH:19][CH:20]=2)=[CH:28][N:27]([CH3:29])[N:26]=1)=[O:31]

Participants

3

Reactant 2

HCID 197686484-(4-fluorophenyl)-1-methyl-1H-pyrazole-3-carboxylic acidHCID 23146350HCID 23146350, compound

Product 1

HCID 17973701HCID 17973701, compound

Procedure

The title compound (0.210 g) was prepared from 2-piperidin-2-ylmethyl-benzothiazole, D30 (0.135 g) and 4-(4-fluorophenyl)-1-methyl-1-H-pyrazol-3-carboxylic acid (0.135 g) using the procedure described in Example 60.

Sources & evidence

ORD record
ord-be57deb1705f4d80b04ab284f5770293
Source dataset
uspto-grants-2011_02
Patent number
US07893090B2

Reaction notes

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