HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(4-Fluorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acid → (RS)-1-(2-Benzo[b]thiophen-2-ylmethyl-piperidin-1-yl)-1-[5-(4-fluoro-phenyl)-2-methyl-thiazol-4-yl]-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(4-Fluorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acid | HCID 22324125 | — |
| Reactant | HCID 23146368 | HCID 23146368 | — |
| Product | (RS)-1-(2-Benzo[b]thiophen-2-ylmethyl-piperidin-1-yl)-1-[5-(4-fluoro-phenyl)-2-methyl-thiazol-4-yl]-methanone | HCID 23146275 | 15.5% |
Reaction Steps
The title compound (40 mg) was prepared from 2-benzo[b]thiophen-2-ylmethyl-piperidine D83 (133 mg) and 5-(4-fluoro-phenyl)-2-methyl-thiazole-4-carboxylic acid (136 mg) according to a procedure similar to that described for Example 4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07893090B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-6d40ccca859f4dc4890872f72a493e20 |
| Source note | uspto-grants-2011_02 |