m-Chloroperbenzoic acid → HCID 58807658, compound

Participants

Reaction Steps

Monomer 1 (30 g, 63.0 mmol, 1 equiv.) was dissolved in methylene choride (200 ml) at room temperature. m-Chloroperoxybenzoic acid (MCPBA, 50 wt %, ca. 22 g, 63.0 mmol, 1 equiv) was then added portion wise. A small exotherm was noted. Once the addition was complete, thin layer chromatography revealed complete conversion after approximately 5 minutes. The crude product was extracted with aqueous sodium hydroxide (2 M) and the organic layer evaporated under reduced pressure to give the crude product as a white solid. Crystallisation from ethanol gave the title compound (19 g, 63%). GC-MS 99.6%, M+ 491 (expected M+ 491)); 31P-NMR (CDCl3) δ (ppm) 34.

Provenance & Evidence