Acetic Acid → Methyl 1-(2-(4-((tert-butoxycarbonyl)(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)amino)piperidin-1-yl)ethyl)-7-methoxy-2-oxo-1,2-dihydroquinoline-3-carboxylate

HRID 136734Notes

Reaction equation

HRID 136734 reaction equation
[C:49]([O:50][BH-:51]([O:52][C:53](=[O:54])[CH3:55])[O:56][C:57](=[O:58])[CH3:59])(=[O:60])[CH3:61].[CH3:4][O:5][c:6]1[cH:7][cH:8][c:9]2[cH:10][c:11]([C:20](=[O:21])[O:22][CH3:23])[c:12](=[O:19])[n:13]([CH2:16][CH:17]=[O:18])[c:14]2[cH:15]1.[CH3:68][C:69](=[O:70])[OH:71].[CH:64]([Cl:65])([Cl:66])[Cl:67].[Cl:1][CH2:2][Cl:3].[Na+:62].[O:24]1[CH2:25][CH2:26][O:27][c:28]2[c:29]1[cH:30][cH:31][c:32]([CH2:34][N:35]([C:36]([O:37][C:38]([CH3:39])([CH3:40])[CH3:41])=[O:42])[CH:43]1[CH2:44][CH2:45][NH:46][CH2:47][CH2:48]1)[cH:33]2.[OH2:63]>>[CH3:4][O:5][c:6]1[cH:7][cH:8][c:9]2[cH:10][c:11]([C:20](=[O:21])[O:22][CH3:23])[c:12](=[O:19])[n:13]([CH2:16][CH2:17][N:46]3[CH2:45][CH2:44][CH:43]([N:35]([CH2:34][c:32]4[cH:31][cH:30][c:29]5[c:28]([cH:33]4)[O:27][CH2:26][CH2:25][O:24]5)[C:36]([O:37][C:38]([CH3:39])([CH3:40])[CH3:41])=[O:42])[CH2:48][CH2:47]3)[c:14]2[cH:15]1

Participants

9

Reactant 8

HCID 176Acetic AcidHCID 923Sodium ionHCID 962WaterHCID 6212ChloroformHCID 6344DichloromethaneHCID 2724942TriacetoxyborohydrideHCID 57815320Tert-butyl (2,3-dihydro-1,4-benzodioxin-6-ylmethyl)(piperidin-4-yl)carbamateHCID 59398418Methyl 7-methoxy-2-oxo-1-(2-oxoethyl)-1,2-dihydroquinoline-3-carboxylate

Product 1

HCID 59398102Methyl 1-(2-(4-((tert-butoxycarbonyl)(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)amino)piperidin-1-yl)ethyl)-7-methoxy-2-oxo-1,2-dihydroquinoline-3-carboxylate

Sources & evidence

ORD record
ord-95cdd267e14e49e8a410a28758d53d9c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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