1-Amino-1-cyclopropanecarbonitrile hydrochloride → HCID 66918396, compound

HRID 1367460Notes

Reaction equation

HRID 1367460 reaction equation
[CH2:1]([O:3][C:4]([C@@H:6]1[CH2:10][C:9](=[O:11])[CH2:8][C@H:7]1[C:12]([OH:14])=O)=[O:5])[CH3:2].Cl.[NH2:16][C:17]1([C:20]#[N:21])[CH2:19][CH2:18]1>>[CH2:1]([O:3][C:4]([C@@H:6]1[CH2:10][C:9](=[O:11])[CH2:8][C@H:7]1[C:12](=[O:14])[NH:16][C:17]1([C:20]#[N:21])[CH2:19][CH2:18]1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 145863631-Amino-1-cyclopropanecarbonitrile hydrochlorideHCID 59619308HCID 59619308, compound

Product 1

HCID 66918396HCID 66918396, compound

Procedure

The reaction of (1R,2R)-4-oxo-cyclopentane-1,2-dicarboxylic acid monoethyl ester and 1-amino-cyclopropanecarbonitrile hydrochloride performed in analogy to example 1, step 8 yielded the title compound as a colorless solid. MS: 265.1 (M+H)+.

Sources & evidence

ORD record
ord-73c9844e628e420688442039ed671b12
Source dataset
uspto-grants-2011_02
Patent number
US07893099B2

Reaction notes

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