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HRID1367533

反应详情

EQUATION

反应方程式

HRID 1367533 的结构方程式

REACTANTS

反应物

1
结构：CO[C@H]1C[C@@H](S(=O)(=O)c2ccc(Br)cc2C(F)(F)F)C[C@@H]1C(=O)NC1(C#N)CC1
HCID59619475

未命名化合物

PRODUCTS

生成物

1
结构：CO[C@@H]1C[C@H](S(=O)(=O)c2ccc(Br)cc2C(F)(F)F)C[C@H]1C(=O)NC1(C#N)CC1
HCID59619295

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)O.CCCCCCC
溶剂HCID21225753

未命名化合物

PROCEDURE

实验过程

Racemic (1R,2R,4R) and (1S,2S,4S)-4-(4-bromo-2-trifluoromethyl-benzenesulfonyl)-2-methoxy-cyclopentanecarboxylic acid (1-cyano-cyclopropyl)-amide (example 58) was subjected to chiral preparative HPLC on Chiralpak AD using heptane/isopropanol 75:25 as eluant. The title compound was eluated as the second peak. MS (EI): 495.1 (M+H)+.