HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxyethanol → HCID 59619317, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxyethanol | HCID 8019 | — |
| Reactant | (1R,2R,4R)-4-(2-Chloro-4-fluoro-benzenesulfonyl)-2-(3,3-difluoro-azetidine-1-carbonyl)-cyclopentanecarboxylic acid (1-cyano-cyclopropyl)-amide | HCID 59619273 | — |
| Product | HCID 59619317 | HCID 59619317 | — |
Reaction Steps
The title compound was prepared in analogy to example 134 using (1R,2R,4R)-4-(2-chloro-4-fluoro-benzenesulfonyl)-2-(3,3-difluoro-azetidine-1-carbonyl)-cyclopentanecarboxylic acid-(1-cyano-cyclopropyl)-amide (example 119 step 4) and 2-methoxyethanol. White solid (37%). MS (EI): 546.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07893099B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-05aeb01c52474a0ca1f1ac93f5642a8d |
| Source note | uspto-grants-2011_02 |