2-Methylpyridine-4-boronic acid → HCID 59619337, compound

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Reaction Steps

The title compound was prepared in analogy to example 62 using 2-picoline-4-boronic acid instead of 2,4-difluorophenylboronic acid and (1R,2R,4R) and (1S,2S,4S)-4-(4-bromo-2-trifluoromethyl-benzenesulfonyl)-2-[(tetrahydro-1,1-dioxo-2H-thiopyran-4-yl)oxy]-cyclopentanecarboxylic acid (1-cyano-cyclopropyl)-amide (example 181) instead of (1R,2R,4R) and (1S,2S,4S)-4-(4-bromo-2-trifluoromethyl-benzenesulfonyl)-2-methoxy-cyclopentanecarboxylic acid (1-cyano-cyclopropyl)-amide. White solid. MS (EI): 624.3 (M−H)−.

Provenance & Evidence