HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylpyridine-4-boronic acid → HCID 66918569, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylpyridine-4-boronic acid | HCID 4192664 | — |
| Reactant | HCID 59619407 | HCID 59619407 | — |
| Reactant | (1S,2S,4S)-4-(4-Bromo-2-trifluoromethyl-benzenesulfonyl)-2-methoxy-cyclopentanecarboxylic acid (1-cyano-cyclopropyl)-amide | HCID 59619475 | — |
| Product | HCID 66918569 | HCID 66918569 | — |
Reaction Steps
The title compound was prepared in analogy to example 62 using 2-picoline-4-boronic acid instead of 2,4-difluorophenylboronic acid and (1R,2R,4R) and (1S,2S,4S)-4-(4-bromo-2-trifluoromethyl-benzenesulfonyl)-2-cyclobutoxy-cyclopentanecarboxylic acid (1-cyano-cyclopropyl)-amide (example 182) instead of (1R,2R,4R) and (1S,2S,4S)-4-(4-bromo-2-trifluoromethyl-benzenesulfonyl)-2-methoxy-cyclopentanecarboxylic acid (1-cyano-cyclopropyl)-amide. White solid. MS (EI): 548.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07893099B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-cf6bc23c178c4645a5c80ea3f0acafae |
| Source note | uspto-grants-2011_02 |