Acetone → tert-Butyl 3-iodopiperidine-1-carboxylate

HRID 136764Notes

Reaction equation

HRID 136764 reaction equation
[CH3:1][S:2]([O:3][CH:6]1[CH2:7][N:8]([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:9][CH2:10][CH2:11]1)(=[O:4])=[O:5].[CH3:28][C:29](=[O:30])[CH3:31].[I-:20].[Na+:19].[Na+:26].[Na+:27].[S:21]([O-:22])([O-:23])(=[O:24])=[S:25]>>[CH:6]1([I:20])[CH2:7][N:8]([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:9][CH2:10][CH2:11]1

Participants

6

Reactant 5

HCID 180AcetoneHCID 923Sodium ion3×HCID 1084Thiosulfate ionHCID 30165Iodide IonHCID 568122N-Boc-3-mesyloxypiperidine

Product 1

HCID 21580769tert-Butyl 3-iodopiperidine-1-carboxylate

Sources & evidence

ORD record
ord-5a6ff07c331f459096544581a52c4248
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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