反应详情

温度

55 °C

THP ether 39 (1.207 g, 3.03 mmol) was dissolved in 95% EtOH (12 ml) and PPTS (76 mg, 0.3 mmol) was added. The mixture was stirred at 55° C. for 4 h, cooled to room temperature and diluted with EtOAc. This mixture was washed with H2O three times, the organic phase was dried over Na2SO4 and evaporated. The residue was chromatographed on silica gel to give 864 mg (91%) of 17-acetoxy-heptadecanol.

1. temperaturecooled to room temperature
2. washThis mixture was washed with H2O three times
3. dry with materialthe organic phase was dried over Na2SO4
4. customevaporated
5. customThe residue was chromatographed on silica gel