2-[[4-[5-(4-fluorophenyl)pyrimidin-2-yl]piperazin-1-yl]sulfonylmethyl]-N-hydroxy-3-methylbutanamide → 2-[[4-[5-(4-chlorophenyl)-2-pyridinyl]piperazin-1-yl]sulfonylmethyl]-N-hydroxy-3-methylbutanamide
Reaction equation
[Cl:32][c:33]1[cH:34][cH:35][c:36](-[c:39]2[cH:40][cH:41][c:42]([N:45]3[CH2:46][CH2:47][N:48]([S:51](=[O:52])(=[O:53])[CH2:54][CH:55]([C:56](=[O:57])[OH:58])[CH:59]([CH3:60])[CH3:61])[CH2:49][CH2:50]3)[n:43][cH:44]2)[cH:37][cH:38]1.[F:1][c:2]1[cH:3][cH:4][c:5](-[c:6]2[cH:7][n:8][c:9]([N:10]3[CH2:11][CH2:12][N:13]([S:14]([CH2:15][CH:16]([CH:17]([CH3:18])[CH3:19])[C:20](=[O:21])[NH:27][OH:28])(=[O:22])=[O:23])[CH2:24][CH2:25]3)[n:26][cH:29]2)[cH:30][cH:31]1>>[NH:27]([OH:28])[C:56]([CH:55]([CH2:54][S:51]([N:48]1[CH2:47][CH2:46][N:45]([c:42]2[cH:41][cH:40][c:39](-[c:36]3[cH:35][cH:34][c:33]([Cl:32])[cH:38][cH:37]3)[cH:44][n:43]2)[CH2:50][CH2:49]1)(=[O:52])=[O:53])[CH:59]([CH3:60])[CH3:61])=[O:57]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-ef5b4296db9640d89c629319c5bb28b4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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