HCID 58724480, compound → HCID 58724484, compound

Participants

Reaction Steps

49.8 mg (0.10 mmol) of 6-[4-(1H-imidazol-2-ylcarbamoyl)-1H-benzoimidazol-2-ylcarbamoyl]-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester in 2 mL of 4 N HCl in dioxane was stirred at r.t. for 2 h. Evaporation of solvents in vacuo gave 1,2,3,4-tetrahydro-isoquinoline-6-carboxylic acid [4-(1H-imidazol-2-ylcarbamoyl)-1H-benzoimidazol-2-yl]-amide in quantitative yield. LCMS: 402 (M+1)+.

Provenance & Evidence