2-amino-5-methyl-3-nitrobenzoic acid → HCID 66940440, compound

HRID 1367933Notes

Reaction equation

HRID 1367933 reaction equation
[NH:1]1[CH:5]=[CH:4][N:3]=[C:2]1[NH:6][C:7]([C:9]1[C:17]2[NH:16][C:15]([NH2:18])=[N:14][C:13]=2[CH:12]=[CH:11][CH:10]=1)=[O:8].N[C:20]1C([N+]([O-])=O)=CC(C)=CC=1C(O)=O>>[NH:3]1[CH:4]=[CH:5][N:1]=[C:2]1[NH:6][C:7]([C:9]1[C:17]2[N:16]=[C:15]([NH2:18])[NH:14][C:13]=2[CH:12]=[C:11]([CH3:20])[CH:10]=1)=[O:8]

Participants

3

Reactant 2

HCID 2319842-amino-5-methyl-3-nitrobenzoic acidHCID 178508178HCID 178508178, compound2×

Product 1

HCID 66940440HCID 66940440, compound

Procedure

0.25 g of 2-amino-6-methyl-1H-benzoimidazole-4-carboxylic acid (1H-imidazol-2-yl)-amide was synthesized according to procedures described for the synthesis of 2-amino-3H-benzoimidazole-4-carboxylic acid (1H-imidazol-2-yl)-amide (intermediate B) starting from 2.5 g (12.7 mmol) of above synthesized 2-amino-5-methyl-3-nitrobenzoic acid. LCMS: 257 (M+1)+.

Sources & evidence

ORD record
ord-064d52c5a7624b0abf178a551b316169
Source dataset
uspto-grants-2011_02
Patent number
US07893267B2

Reaction notes

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