Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Sodium ethoxide | HCID 2723922 | — |
| Reactant | Methyl 3-amino-5-fluoro-2-nitrobenzoate | HCID 58724451 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 66940621 | HCID 66940621 | — |
Reaction Steps
5.0 g (23.3 mmol) of 3-amino-5-fluoro-2-nitro-benzoic acid methyl ester was dissolved in ethanol and treated with 2.6 g (25.6 mmol) of triethylamine and 1.8 g (25.6 mmol) of NaOEt. The reaction was heated at 60° C. for 0.5 h to produce 3-amino-5-ethoxy-2-nitro-benzoic acid ethyl ester. LCMS: 255 (M+1)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07893267B2 |
|---|
| Source dataset | uspto-grants-2011_02 |
|---|
| ORD ID | ord-2abc8f152b0a40aeb4e52387f205b442 |
|---|
| Source note | uspto-grants-2011_02 |
|---|
