HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyanogen Bromide → HCID 66940226, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyanogen Bromide | HCID 10476 | — |
| Reactant | methyl 2-amino-1H-benzo[d]imidazole-4-carboxylate | HCID 24730367 | — |
| Reactant | 2,3-Diamino-5-ethoxy-benzoic acid ethyl ester | HCID 66940723 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 66940226 | HCID 66940226 | — |
Reaction Steps
4.0 g (17.9 mmol) of 2,3-diamino-5-ethoxy-benzoic acid ethyl ester was subjected to a similar cyclization condition as illustrated in intermediate A by using 5.7 g (53.7 mmol) of BrCN in methanol to produce 2-amino-6-ethoxy-1H-benzoimidazole-4-carboxylic acid ethyl ester. LCMS: 250 (M+1)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07893267B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-2e0206f73ae64aa590ab95b36b46c137 |
| Source note | uspto-grants-2011_02 |